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Construction of BLOSUM80 Matrix for a Specific DNA Database, Assignments of Mathematics

This exercise provides a dna database consisting of 8 blocks and asks to construct a blosum80 matrix for this database. The process of constructing the matrix involves creating a frequency matrix, computing log-odds scores, and normalizing the scores to obtain the blosum80 matrix. This exercise is useful for understanding the concepts of sequence alignment and scoring matrices in bioinformatics.

Typology: Assignments

Pre 2010

Uploaded on 08/18/2009

koofers-user-kil
koofers-user-kil 🇺🇸

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Name: _______________________
MATH 4370/ CS 4390
Topics in Bioinformatics Exercise 8
Due 3/9/2004
If you are given a "database" consisting of 2 DNA blocks:
A C A _ G A C G G C T
A C C C C T C G G A T
A T G T A T C G G A A
A C G T A
A C T T A
Construct a BLOSUM80 matrix for this database. Show your work in detail.

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Name: _______________________ MATH 4370/ CS 4390 Topics in Bioinformatics Exercise 8 Due 3/9/ If you are given a "database" consisting of 2 DNA blocks: A C A _ G A C G G C T A C C C C T C G G A T A T G T A T C G G A A A C G T A A C T T A Construct a BLOSUM80 matrix for this database. Show your work in detail.