Download Organic Chemistry Exam - CHEM 231A, Test #4 and more Exams Organic Chemistry in PDF only on Docsity!
Name:
Organic Chemistry - CHEM 231A
Test # November 5, 2001
- Provide answers to the following questions: (32 points)
1a. What is the importance of a leaving group in substitution and/or elimination reactions (8 points)
1b. What role does solvent play in the Sn2 reaction. Explain. (8 points)
1c. What determines product distribution in 1st^ order reactions. Explain. (8 points)
1d. What are the stereochemical considerations in the Sn2 Reaction. Describe each and explain their
origin and effect on the reaction. (8 points)
- Predict products for the following reactions and briefly explain your answer. (5 @ 8 pts = 40 points)
2a.
Cl
NaCN / Acetone
2b.
O S
O
O
NaCl (1 eq) / H 2 O
2c.
Cl
MeOH Reflux
2d. Br
O
DMF
K
2e. Br
H 2 O
- Consider the following problem: (26 points)
O
S
O
O
H 3 C
Make this from this
4a. Conduct a retrosynthetic analysis for the above problem. It will be beneficial to think about more than one method to make the desired molecule; the various methods do not have to be completely correct, but rather should show that you have thought of alternative routes.. ( points)
4b. Using the best approach from problem 4a, synthesize the desired molecule. Mechanism are not required, but reagents and conditions are required. (13 points)
