Docsity
Docsity

Prepare for your exams
Prepare for your exams

Study with the several resources on Docsity


Earn points to download
Earn points to download

Earn points by helping other students or get them with a premium plan


Guidelines and tips
Guidelines and tips

Solved Midterm Exam 1 - Introduction to Genetics | EEMB 129, Exams of Genetics

Material Type: Exam; Professor: Hodges; Class: INTRO GENETICS; Subject: Ecology, Evolution & Marine Biology; University: University of California - Santa Barbara; Term: Winter 2011;

Typology: Exams

2010/2011

Uploaded on 03/07/2011

michaelwilson2008
michaelwilson2008 🇺🇸

5

(4)

10 documents

1 / 5

Toggle sidebar

This page cannot be seen from the preview

Don't miss anything!

bg1
EEMB 129 Midterm I Name__________________________
2011 Perm #__________________________
Read each question carefully before you answer it.
Make sure that you show your work.
1.#(12#pts#total)#In#pea#plants,#tall#plant#height#(T)#is#dominant#over#short#(t).#Pure;
breeding#tall#and#short#plants#are#crossed.#
A. #(4#pts)#What#will#be#the#genotype#and#phenotype#of#the#F1?#
Tt#$#Tall#
#
B. (4 pts) If the F1 is selfed and 400 F2 plants are raised, how many plants would be
expected in each phenotypic class?
300##Tall# # 100#$#Short#
#
C. #(4#pts)#How#many#of#the#F2#plants#would#be#expected#to#be#pure#breeding#
when#selfed?#
200#(100#TT#and#100#tt)#
#
#
2. (12 pts) Below is a pedigree of a human genetic disease in which stricken individuals
are represented by solid color.
a. Is the disease caused by a dominant or recessive allele?
b. Indicate the genotypes of as many individuals as possible.
c. Calculate the probability an offspring of the cousin marriage 1 x 4 will have the
disease.
pf3
pf4
pf5

Partial preview of the text

Download Solved Midterm Exam 1 - Introduction to Genetics | EEMB 129 and more Exams Genetics in PDF only on Docsity!

2011 Perm #__________________________

Read each question carefully before you answer it.

Make sure that you show your work.

  1. (12 pts total) In pea plants, tall plant height (T) is dominant over short (t). Pure-­‐ breeding tall and short plants are crossed. A. (4 pts) What will be the genotype and phenotype of the F1? Tt Tall B. (4 pts) If the F1 is selfed and 400 F2 plants are raised, how many plants would be expected in each phenotypic class? 300 – Tall 100 Short C. (4 pts) How many of the F2 plants would be expected to be pure breeding when selfed? 200 (100 TT and 100 tt)
  2. (12 pts) Below is a pedigree of a human genetic disease in which stricken individuals are represented by solid color. a. Is the disease caused by a dominant or recessive allele? b. Indicate the genotypes of as many individuals as possible. c. Calculate the probability an offspring of the cousin marriage 1 x 4 will have the disease.

2011 Perm #__________________________

  1. (10 pts) Four genes are linked to one another in the following manner: A—B 15 map units C—B 15 map units A—C 10 map units C—A 10 map units A—D 35 map units C—D 35 map units B—C 25 map units B—A 25 map units C—D 25 map units A—D 25 map units A. Draw a linkage map of genes A, B, C & D B__________A____C__________________D B_________C____A_______________D 15 10 25 15 10 25 | 50 | | 50 | B. A BD/BD individual was crossed with a bd/bd individual. If one of their offspring was used in a testcross, what would be the expected frequencies for each type of gamete that it produces? 1 BD BD/bd 1 Bd 1 bD 1 bd
  2. (10 pts) a. What is the formula for calculating a X^2 statistic? X^2 = SUM (OBS – EXP)^2 EXP b. If you used X^2 to test whether or not two genes were linked and obtained the following values, what would you conclude? X^2 = 7.7, df = 3 X^2 = 7.9, df = 3 NOT SIG, UNLINKED SIG, LINKED You may use the following table: P -­‐-­‐-­‐-­‐|-­‐-­‐-­‐-­‐ df 0 .995 0.975 0.9 0.5 0.1 0.05 0.25 0.01 0. 1 0.000 0.000 0.016 0.455 2.706 3.841 5.024 6.635 7. 2 0.010 0.051 0.211 1.386 4.605 5.991 7.378 9.210 10. 3 0.072 0.216 0.584 2.366 6.251 7.815 9.348 11.345 12. 4 0.207 0.484 1.064 3.357 7.779 9.488 11.143 13.277 14.

2011 Perm #__________________________

  1. (10 pts). An anteater is dihybrid at the "A" and the "B" genes, which are located on different chromosomes. Indicate (by circling the number) which of the following diagrams do not represent a stage of meiosis for this anteater? For each of the remaining diagrams, name the stage of meiosis they represent and whether crossing over has occured.

2011 Perm #__________________________

  1. (4 pts) Suppose you discovered a new mutation in mice that caused a curved spine. You noticed that this mutation was only seen in females. When curved-­‐spine females were crossed with normal males, the progeny were always recovered in the ratio: 1/3 curved-­‐spine females, 1/3 normal females, 1/3 normal males. Explain the genetic basis for this ratio. The gene is X linked; the curved spine allele is dominant to the normal allele in heterozygotes but causes lethality in hemizygous males. Xc+Xc^ x Xc+Y > Xc+Xc+, Xc+Xc, Xc+Y, XcY (dies)
  2. (6 pts) Two individuals homozygous for different alleles at the A-­‐gene (A or a) and at the B-­‐gene (B or b) were crossed (both loci exhibit complete dominance). Their F1 progeny were used in a testcross and produced the following phenotypic classes: Phenotype class Number Number AB 160 40 Ab 40 160 aB 50 150 ab 150 50 Without doing statistics, what do you suspect were the genotypes of the original parental individuals and the F1? P AABB x aabb P AAbb x aaBB F1 AB/ab F1 Ab/aB