PHAR 100 – Exam Questions and Correct Answers (Verified) University of California, San
Francisco (UCSF) A+ Grade Academic Year 2025-2026
Phase |One |Drug |Trial |- |answersSmall |number |of |people
Absorption, |distribution, |elimination, |and |adverse |effects |are |monitored
Phase |Two |Drug |Trial |- |answersSmall |number |of |people
Determines |if |drug |is |effective |in |treatment
Phase |Three |Drug |Trial |- |answersLarge |number |of |people
Safety |of |drug |is |carefully |studied
Potency |- |answersAmount |of |drug |that |must |be |given |to |obtain |a |response
Efficacy |- |answersMaximum |effect |of |the |drug
Paul |Ehrlich |- |answersOrganoarsenic |compounds
Salvarsan: |syphilis |treatment
Gerhard |Domagk |- |answersSulfonamides
Prontosil: |streptococcus
Antimetabolites |- |answersAct |against |substances |required |for |metabolism |of |an |organism |
Example: |sulfanilamide
Sulfanilamide |- |answersAntimetabolite
Therapeutic |Index |- |answersLethal |Dose |(Toxicity) |÷ |Effective |Dose
Higher |means |safer
Parenteral |Routes |- |answersIntramuscular
Subcutaneous
Intravenous
Enteral |Routes |- |answersMouth
Rectal
Under |Tongue
Drug |Dependence |- |answersPhysical |dependence |
Psychological |dependence
