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anxiety disorders treatment - ✔✔✔ Correct Answer > -non-activating antidepressants area good place to start. for this disorder first line treatment anxiety disorders - ✔✔✔ Correct Answer > SSRIFluoxetine (Prozac), sertraline (Zoloft), and paroxetine (Paxil) anorexia nervosa - ✔✔✔ Correct Answer > An eating disorder characterized by an obstinate and willful refusal to eat, a distorted body image, and an intense fear of being fat Benzodiazepines - ✔✔✔ Correct Answer > Withdrawal can be dangerous, even deadly. Stopping abruptly is not advised. Symptoms of agitation, tension, irritability, and sz. may occur
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anxiety disorders treatment - ✔✔✔ Correct Answer > - non-activating antidepressants area good place to start. for this disorder first line treatment anxiety disorders - ✔✔✔ Correct Answer > SSRI- Fluoxetine (Prozac), sertraline (Zoloft), and paroxetine (Paxil) anorexia nervosa - ✔✔✔ Correct Answer > An eating disorder characterized by an obstinate and willful refusal to eat, a distorted body image, and an intense fear of being fat Benzodiazepines - ✔✔✔ Correct Answer > Withdrawal can be dangerous, even deadly. Stopping abruptly is not advised. Symptoms of agitation, tension, irritability, and sz. may occur
anxiety disorders - ✔✔✔ Correct Answer > psychological disorders characterized by distressing, persistent anxiety or maladaptive behaviors that reduce anxiety TCAs often effective but with riskier SE may interfere with psychotherapy in TX of AD - ✔✔✔ Correct Answer > Benzodiazepines- short acting Alprazolam are most abusable Rapid onset BZD - ✔✔✔ Correct Answer > used for acute panic disorder BZD with long half- life (20- 80 hours) - ✔✔✔ Correct Answer > Diazepam (avoid in elderly) BEERS criteria - ✔✔✔ Correct Answer > A list of medications that are generally considered inappropriate when given to elderly people
BZD in treatment of OCD - ✔✔✔ Correct Answer > Xanax, Valium, Klonipin Trauma and Dissociative Disorders - ✔✔✔ Correct Answer > Consider and treat and comorbid disorders as well Trauma and Dissociative Disorders first line pharmocology - ✔✔✔ Correct Answer > Antidepressants Psychotherapy are treatment of choice Dissociative disorders - ✔✔✔ Correct Answer > the degree of insight the patient has is crucial to the outcome of psychotherapy Acute anxiety - ✔✔✔ Correct Answer > First line for acute panic may be short term benzo use. short acting benzos cause rebound anxiety and are the most abused
DID- Dissociative identity disorder - ✔✔✔ Correct Answer > may consider multi pronged approach to treatment but strongly linked to childhood trauma so treating underlying PTSD s/s is often helpful DID - ✔✔✔ Correct Answer > discourage use of BZD DID - ✔✔✔ Correct Answer > beta blockers and alpha blockers useful for reducing sympathetic nervous system activation Prazosin - ✔✔✔ Correct Answer > alpha 1 blocker helpful for nightmares and flashbacks Meds for anorexia - ✔✔✔ Correct Answer > Prozac Anafranil Pariactin Thorazine Zyprexa
SSRI side effects - ✔✔✔ Correct Answer > BAD SSRI B - Body weight increase; A - Anxiety/Agitation; D - Dizziness; Dry mouth S - Serotonin syndrome; S - Stimulated CNS; R - Reproductive/Sexual dysfunction I - Insomnia; antidepressants used in eating disorders - ✔✔✔ Correct Answer > SSRIs (high doses), TCAs TCAs - ✔✔✔ Correct Answer > tricyclic antidepressants TCA side effects - ✔✔✔ Correct Answer > 3Cs - cardiotoxicity, coma, convulsions
antihistamine - weight gain, sedation anti adrenergic - orthostasis, reflex tachy, arrythmias, wide QRS/QT/PR anti-muscarinic - dry mouth, constipation, urinary retention, blurred vision, tachycardia, narrow angle glaucoma serotoninergic side effects - erectile/ejaculatory dysfunction in males, anorgasmia in females lethal in overdose weight gain seizures meds to treat Binge Eating Disorders - ✔✔✔ Correct Answer > Vyvanse (lisdexamfetamine) pharmacology indications for anorexia nervosa - ✔✔✔ Correct Answer
No medications are approved to treat anorexia because none has been found to work very well. However, antidepressants or other psychiatric medications can help treat other mental health disorders you may also have, such as depression or anxiety.
Buproprion contraindications - ✔✔✔ Correct Answer > increases risk of seizures, anorexia, bulimia. avoid with any condition that increases seizure-- abrupt etoh withdrawl, head injuries. antidepressants in binge eating disorders - ✔✔✔ Correct Answer > SSRI are first line if you are going to choose an antidepressant to treat as they are often very co-morbid with depression and anxiety disorders If a patient has both eating disorder and comorbid depression or anxiety, treatment should follow indications for the comorbidity- ex. if they have OCD comorbid with anorexia nervosa then what ( ?) would be indicated for the OCD should be your choice - ✔✔✔ Correct Answer
SSRI Insomnia treatment - ✔✔✔ Correct Answer > nonpharmacologic treatments for insomnia include sleep hygeine, stimulus control, relaxation, sleep restriction, and cognitive behavioral therapy. Stimulus
control focuses on eliminating stimulating bedroom activities and getting into bed only when sleepy. benzodiazepine hypnotics (tx of insomnia) - ✔✔✔ Correct Answer > Diazepam, Midazolam, Zolazepam, Triazolam, flurazepam, temazepam Potentiates the inhibitory action of GABA ( inhibitory neurotransmitter that reduces feelings of fear and anxiety). Activation of the receptor causes an influx of Cl- ion movement into the neuron and hyperpolarization and inhibition of membrane depolarization Benzodiazepine hypnotics affect - ✔✔✔ Correct Answer > REM sleep, tolerance, risk of abuse, rebound insomnia Non-BZD hypnotics for insomnia - ✔✔✔ Correct Answer > Zolpidem (Ambien) Zaleplon (Sonata) Eszopiclone (Lunesta)
GHB sodium oxybate - ✔✔✔ Correct Answer > CIII What is GHB - ✔✔✔ Correct Answer > Sodium oxybate, sold under the brand name Xyrem among others, is a medication used to treat two symptoms of narcolepsy: sudden muscle weakness and excessive daytime sleepiness. Treatment of restless leg syndrome - ✔✔✔ Correct Answer > Mild/intermittent sxs:
Flurazepam half life - ✔✔✔ Correct Answer > 2.3 hours Zoldipem half life - ✔✔✔ Correct Answer > 2.5- 3 hours Zaleplon half life - ✔✔✔ Correct Answer > 1 hour rebound insomnia - ✔✔✔ Correct Answer > in a person with insomnia, the worsened sleep problems that can occur when medications are used to treat insomnia and then withdrawn rebound insomnia and effect on REM sleep - ✔✔✔ Correct Answer > Like rebound sleep in general, REM rebound sleep3 usually occurs in response to sleep deprivation or stress. REM rebound can also occur in response to a suppression of REM sleep in particular Narcolepsy treatment options - ✔✔✔ Correct Answer > Stimulants. Drugs that stimulate the central nervous system are the primary
treatment to help people with narcolepsy stay awake during the day. modafinil (Provigil) or armodafinil (Nuvigil) first for narcolepsy
Amitriptyline Nortriptyline (Pamelor) Protriptyline (Vivactil) Doxepin (Silenor) Imipramine (Tofranil) Clomipramine (Anafranil) Desipramine (Norpramin) SNRIs - ✔✔✔ Correct Answer > Venlafaxine (Effexor) Duloxetine (Cymbalta) Some SNRIs, such as venlafaxine (Effexor XR), duloxetine (Cymbalta, Drizalma Sprinkle), milnacipran (Savella) and desvenlafaxine (Pristiq), may help relieve chronic pain. People with chronic pain often develop depression along with their chronic pain. Venlafaxine and duloxetine offer the advantage of being effective for depression and anxiety at the same dosages useful for treating pain.