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Nephrotic Syndrome Vs Nephritic. Syndrome ... Understand and define nephrotic and nephritic syndromes. ... Describe the complications of nephrotic and.
Typology: Study notes
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Dr. T.S. Srinath Kumar MD Group Head, Narayana Hrudayalaya President, Society Emergency Medicine India Member - Special Advisory Board for Emergency Medicine, DNB Associate Editor – National Journal of Emergency Medicine
Understand and define nephrotic and nephritic syndromes. Describe the initial investigations and management of nephrotic and nephritic syndromes. Describe the complications of nephrotic and nephritic syndromes.
NEPHROTIC
Proteinuria
3gm/day Hypoalbuminemia <2.5gm/dl Hyperlipidemia
Oedema BP normal/raised Leukonychia Breathlessness: Pleural effusion, fluid overload, AKI DVT/PE/MI Eruptive xanthomata/ xanthalosmata
Young, fit 24 year old male complaining of frothy urine. 10 year old boy with puffy eyes. 74 year old female with multiple co-morbidities and swollen ankles.
Primary glomerulonephritis Minimal change disease (80% paeds cases) Focal segmental glomerulosclerosis (most common cause in adults) Membranous glomerulonephritis
Secondary glomerulonephritis Diabetic nephropathy Sarcoidosis Autoimmune: SLE, Sjogrens Infection: Syphilis, hepatitis B, HIV Amyloidosis Multiple myeloma Vasculitis Cancer Drugs: gold, penicillamine, captopril, NSAIDs
Conservative Monitor U&E, BP, fluid balance, weight Salt and fluid restriction Treat underlying cause
Decrease Glomerular pressure Contain antifibrotic effects For controlling edema Combination drugs more useful For Hyperlipidemia and Hyper triglyceredemia
