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Lab Quiz #5 with Answer Key - Genetics Lab | BIOL 3110L, Quizzes of Genetics

Material Type: Quiz; Professor: Biliran; Class: Genetics Lab; Subject: Biology; University: Xavier University of Louisiana; Term: Fall 2009;

Typology: Quizzes

Pre 2010

Uploaded on 12/09/2009

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Bio3110 Lab quiz#5
Name:_______________________________
Section:____________________________
I. Multiple choice ( 2pts each)
1. Mutations maybe classified based on its impact on protein sequence. Which of the
following leads to premature termination of protein synthesis?
A. Missense mutation
B. Neutral mutation
C. Silent mutation
D. Nonsense mutation
E. None of the above
2. A back mutation or reverse mutation is point mutation that restores the original sequence
and hence the original phenotype. This type of mutation is illustrated in which phenotype
of the D7 S. cerevisiae strain?
A. Red/pink colonies
B. Isoleucine auxotrophy
C. Isoleucine prototrophy
D. Tryptophan prototrophy
E. None of the above
3. Which of the following statement(s) is (are) true with regards to mutation?
A. Spontaneous mutations are common due to the inefficiency of DNA repair
mechanisms
B. Mutations found in somatic cells may be passed on to future generations
C. Compounds or chemicals that are known to be mutagenic may be considered
carcinogenic
D. A and B
E. None of the above
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Bio3110 Lab quiz#

Name:_______________________________

Section:____________________________

I. Multiple choice ( 2pts each)

  1. Mutations maybe classified based on its impact on protein sequence. Which of the following leads to premature termination of protein synthesis? A. Missense mutation B. Neutral mutation C. Silent mutation D. Nonsense mutation E. None of the above
  2. A back mutation or reverse mutation is point mutation that restores the original sequence and hence the original phenotype. This type of mutation is illustrated in which phenotype of the D7 S. cerevisiae strain? A. Red/pink colonies B. Isoleucine auxotrophy C. Isoleucine prototrophy D. Tryptophan prototrophy E. None of the above
  3. Which of the following statement(s) is (are) true with regards to mutation? A. Spontaneous mutations are common due to the inefficiency of DNA repair mechanisms B. Mutations found in somatic cells may be passed on to future generations C. Compounds or chemicals that are known to be mutagenic may be considered carcinogenic D. A and B E. None of the above
  1. Mutagenic treatment of the wild type D7 S. cerevisiae strain results in the formation of red or pink colonies. Which type of mutation results in this type of phenotypic change? A. Reverse/ point mutation B. Mitotic gene conversion C. Gap/repair mutation D. Mitotic crossing over E. None (wild type)
  2. Mutagenic treatment of the wild type D7 S. cervisiae strain results in tryptophan prototrophy. Which type of mutation results in this type of phenotypic change? A. Reverse/point mutation B. Mitotic gene conversion C. Gap repair mutation D. Mitotic crossing over E. None (wild type) II
  3. Following treatment with a known suspected mutagen, the wild type D7 S. cerevisiae maintains its isoleucine auxotrophy phenotype. Provide an explanation to your findings. ( 5pts) The fact that the phenotype of the D7 S. cerevisiae strain did not change from isoleucine auxotrphy to isoleucine prototrophy indicate that the suspected mutagen did not induce mutation following gene conversion and repair mechanism. Such limited data does not exclude the possibility the sample is a mutagen.