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Alzheimer's disease - correct answer>>-amyloid hypothesis: idea that Alzheimer's disease is caused by the accumulation of beta-amyloid proteins in the frontal & temporal lobes -screening: mini mental status exam (MMSE) assessment tool -treatment goal: slow cognitive decline as there is no cure -mild-moderate dementia: cholinesterase inhibitors (donepezil & rivastigmine -severe dementia: NMDA antagonists (memantine) -must know facts: leading cause of dementia -presentation: gradual loss of cognitive function -remember your 4 "A" cardinal symptoms... 1. Agnosia: inability to process sensory information (think of your 5 senses) ex: incontinence, taste, smell, sounds 2. Apraxia: loss of voluntary motor skills (purposeful movements) 3. Aphasia: expressive (knows what they want to say but can't say it) vs receptive (cannot perceive what is being said to them)
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Alzheimer's disease - correct answer>>-amyloid hypothesis: idea that Alzheimer's disease is caused by the accumulation of beta-amyloid proteins in the frontal & temporal lobes
Selective norepinephrine reuptake inhibitors (SNRIs) - correct answer>>-mechanism of action: blocks pre-synaptic serotonin & norepinephrine re-uptake