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Material Type: Exam; Professor: Werner; Class: Life Chemistry II; Subject: Chemistry; University: Lake Superior State University; Term: Fall 2004;
Typology: Exams
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CHEM 105 Life Chemistry II Fall 2004 Lecture MWF 11-11:50AM, Rm. 205 Crawford Hall Lab Mon. (sect. A) 6-8PM or Tue. (sect. B) 2-4PM. 308 Crawford Hall Dr. M. Werner office: CRW 314, phone: 635-2281 email: mwerner@lssu.edu Office Hours: Monday, Wednesday, and Friday 10-11AM, and Monday 2-4PM, or by appointment Text: General, Organic, and Biological Chemistry by H.S. Stoker 3nd^ ed. 2004 *Week of: Topics Chapters Aug. 30 Review Bonding, Electronegativity, Polarity 5.8-5. Sept. 1 Structure drawing and geometry 12 3 Properties and nomenclature of alkanes 12 Sept. 6 NO CLASS 8 NO CLASS 10 Intro. to Functional Groups 13- Sept. 13 Aromatic Hydrocarbons 15 Oxygen in organic compounds 17 Reactions of alcohols, rxn. mechanisms Sept. 20 Carbonyls 22 Carbonyls, Tetrahedral intermediates 24 Exam 1, emphasizing chapters 12-15 Friday during class Sept. 27 Carboxylic acids, review pKa 16 and 10.5-10. 29 CA derivatives 16- Oct. 1 Formation of esters Oct. 4 Amines 6 Amides 8 Synthetic Drugs and Applications lecture Oct. 11 Organic Review lecture 13 Exam 2, emphasizing chapters 16-17 Wednesday during class 15 NO CLASS Oct. 18 Stereochemistry, intro. to carbohydrates 18 20 Carbohydrates, nomenclature, drawing 18 22 Reactions of Carbohydrates 18 Oct. 25 Nucleic acids, properties, base pairing 22 27 DNA replication 22 29 Protein synthesis and the genetic code 22 Nov. 1 Amino acids, peptide bonds, Protein structure 20 3 Protein Folding, Enzymatic catalysis 20, 21 5 Enzyme mechanism 21 Nov. 8 Enzyme inhibition and medical applications 21 10 Medically relevant enzymes - Pharmacology lecture 12 Exam 3, emphasizing chapters 18, 20-22 Friday during class Nov. 15 Introduction to carbohydrate metabolism 24 17 Fates of Pyruvate 24 19 Gluconeogenesis 24 Nov. 22 Important Compounds in Metabolism 23 Nov. 23-28 THANKSGIVING BREAK NO CLASS Nov. 29 Citric acid cycle 23 Dec. 1 Electron transport chain, ATP production 23 3 Review of metabolic pathways 23 and 24 Dec. 6 Exam 4, emphasizing chapters 23 and 24 Monday during class 8 Class Review session lecture 10 Class Review session lecture Dec. 13 Comprehensive ACS Final Exam Mon. Dec. 13th^ 10AM-12PM *This is a tentative schedule and may be modified as I deem necessary.
Objective: My aim is to introduce you to the concepts necessary for understanding how the biological world works at its most basic level, the chemical level. I realize that most of you have varied career plans, but if I can excite just one of you enough to want to apply chemistry in your career, I have succeeded in my objective. Format : This course will follow the text quite closely although the order of chapters may be rearranged. Lectures will be 50 min containing copious examples of real world applications of organic and biochemistry. Your active participation in the lecture is appreciated and encouraged, however, if time is a limitation, I may ask you to see me after lecture. It is vital that you read the material prior to coming to class. Do not bring your text to class. Why? Focus your attention on the lecture notes and the discussion going on in class. Don’t bother trying to flip through the text to see how my presentation differs. BE PREPARED TO TAKE YOUR OWN NOTES! I suggest a loose-leaf note book. Study Habits:
CHEM 105 Life Chemistry II Laboratory Fall 2004 Lab Mon.(sect. A) 6-8PM (Dr. Iretski) and Tue.(sect. B) 2-4PM (Dr. Westrick) 308 Crawford Hall Dr. M. Werner office: CRW 314, phone: 635-2281 email: mwerner@lssu.edu Required Lab text : “ Brenstein/Hinckley: General, Organic, Biochemistry Experiments” Required Lab Extras : Lab Notebook with gridded carbon copy pages (available in the Book Store), safety goggles or glasses. The purpose of the laboratory in CHEM 105 is to acquaint you with laboratory techniques encountered in organic and biochemical research and to give you practical experience in performing these types of experiments. The experiments were selected based on the techniques used and to some extent application to lecture material. You will need to purchase a lab notebook with gridded duplicate pages. Goggles or safety glasses are
Week of: Experiment Aug. 30 NO LAB Sept. 6 NO LAB Sept. 13 Check-in, Buffers Sept. 20 ☺ Acetic Acid in Vinegar Sept. 27 Molecular Models of Hydrocarbons Oct. 4 ☺ Synthesis of Esters Oct. 11 ☺ Synthesis of Aspirin Oct. 28 Quantative determination of glucose Oct. 25 Homemade Soap Nov. 1 ☺ Extraction of Caffeine from Coffee Nov. 8 Titration of Amino Acids Nov. 15 Photometric Determination of Invert Sugar Nov 22 No lab , Thanksgiving Nov. 29 ☺ Effect of Enzyme Concentration on Reaction Velocity Dec. 9 No Lab ☺ = Quiz in your lab section for that week. In order to complete the labs in the allotted time, you must be familiar with the lab procedure before the start of the lab period. Read the complete experiment and do the prelab questions (called Study Questions) before coming to lab. Prelab questions will be turned in at the beginning of each lab and graded as part of you lab grade. Keep in mind, in this laboratory, it is important that you understand what you are doing at each step and why you are doing it. If you are in doubt about what to do, ask, and remember that old lab axiom, “Never throw anything away.”
grading purposes, the best 10 lab grades will be counted out of 11. Missed labs cannot be made up and will be recorded as a zero. Tardiness will result in loss of points (every 5 min late equals 2 pts) and you may miss important last minute instructions for the experiment. For most of the experiments, you will work with a partner; make sure it is a team effort. Labs turned in more than one week late will not be graded and will simply be returned. Lab Notebook: It is imperative that you maintain a complete notebook. This note book is to be separate from the lab manual. Anyone should be able to take your notebook and understand what was done, what results were obtained, and repeat the experiment. Write in the lab notebook with ballpoint pen, crossing through errors. Do not remove original pages from the notebook. I will collect the duplicate pages, except
for the results and discussion, at the end of lab. Results and discussion will be due the following week along with your analysis sheets from the lab manual. The lab notebook is to contain: