ENTEROCOLITIS
NECROTIZANTE Dr. Elias Sandino Rosette
Mendoza
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Enterocolitis necrotizante en el neonato, Slides of Medicine
Enterocolitis necrotizante en el neonato
Typology: Slides
2024/2025
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ENTEROCOLITIS
NECROTIZANTE
Dr. Elias Sandino Rosette Mendoza
DEFINICIÓN
Es una lesión inflamatoria aguda del intestino delgado distal y a menudo del intestino grueso próximal. Necrosis coaguladora segmentaria Hemorragia focal Gas intramural Eichenwald E, Hansen A, Martin C, Stark A, Cloherty y Stark Manual de Neonatología, 8va Ed,
FACTORES DE RIESGO
Patel A, Panagos P, Silvestri J, Reducing Incidence of Necrotizing Enterocolitis, Clin Perinatol 2017;
PREMATUREZ
- Motilidad disminuida
- Permeabilidad intestinal aumentada
- Reducción en la lamina propia de linfocitos e IgA
Chandran S, Medications that increase osmolaty and compromise the safety of enteral feeding in preterm infan ts, Neonatology 2017; 111: 309-
MICROBIO
MA
Uso de IBP y bloqueadores de la histamina- Uso de antibioticos empíricos en los primeros días de vida. Colonización de la SOG. Collins A, Weitkamp J, Wynn J, Why are preterm newborns at increased risk ofinfection?, Arch Dis Child Fetal Neonatal, Ed 2018; 0: F1–F
OTROS FACTORES
El peso al nacer y la mala colocación del CVU como factores de riesgo independientes asociados con ECN.
PATOGÉNESIS
Niemarkt H, Necrotizing enterocolitis, gut microbiota, and brain development: role of the brain-gut axis, Neonatology 2019;
DIAGNÓSTICO
Dominguez K, Moss R, Necrotizing Enterocolitis, Clin Perinatol 2012; 39: 387-401.
RADIOGRAFÍA
íleo Edema interasa Neumatosis intestinal Neumatosis portal Eaton S, Rees C, Hall N, Current research on the epide miology, pathogenesis, and management of necrotizi ng enterocolitis. Nenatology 2017; 111: 423-430.
Kim J, Necrotizing enterocolitis and bowel ultrasound, Clin Perinatol 2018.
TRATAMIENTO
Inicio de
antibióticos
Cese de la
alimentació
n
Descompres
ión gástrica
Indicaciones de tratamiento quirurgico Neumoperitoneo Neumatosis intestinal difusa Gas en vena porta Asa fija Deterioro clínico Eichenwald E, Hansen A, Martin C, Stark A, Cloherty y Stark Manual de Neonatología, 8va Ed,