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Chemotherapy and Biotherapy Guidelines - ONS 942p Exam Questions and Answers 2024/2025, Exams of Nursing

University of GlasgowNursing

Chemotherapy and Biotherapy Guidelines - ONS 942p Exam Questions and Answers 2024/2025 nadir - Correct Answer-lowest blood cell count after chemotherapy, 10-14 days but varies with individual agents

Typology: Exams

2023/2024

Available from 07/06/2024

NurseMaryK
NurseMaryK 🇬🇧

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Chemotherapy and Biotherapy
Guidelines - ONS 942p Exam
Questions and Answers 2024/2025
nadir - Correct Answer-lowest blood cell count after chemotherapy, 10-14
days but varies with individual agents
cisplatin - Correct Answer-ototoxic --> report
tinnitus nephrotoxic --> monitor BUN and
creatinine depletes K and Mg -->
replacement prior/after
cytoxan - Correct Answer-hemorrhagic cystitis
>3000ml/day fluid intake unless
contraindicated void q2-4 hours day, q4
hours night
can also cause sinus drainage, slow infusion
oxaliplatin - Correct Answer-hang with
D5W cold sensitivity
(Ixnay on the ice, okay?)
irinotecan - Correct Answer-
diarrhea (I run to the can)
nephrotoxic - Correct Answer-avastin - protein
in urine cisplatin
zometa
hypersensitivity reactions - Correct
Answer-taxol rituxan and other MAbs
herceptin
zometa - Correct Answer-know
creatinine prior run over at least 15
mins
osteonecrosis of jaw
taxol - Correct Answer-titrate first couple
doses peripheral neuropathy
cryotherapy
need filtered
pf3
pf4
pf5
pf8

Partial preview of the text

Download Chemotherapy and Biotherapy Guidelines - ONS 942p Exam Questions and Answers 2024/2025 and more Exams Nursing in PDF only on Docsity!

Chemotherapy and Biotherapy

Guidelines - ONS 942p Exam

Questions and Answers 2024/

nadir - Correct Answer-lowest blood cell count after chemotherapy, 10- days but varies with individual agents cisplatin - Correct Answer-ototoxic --> report tinnitus nephrotoxic --> monitor BUN and creatinine depletes K and Mg --> replacement prior/after cytoxan - Correct Answer-hemorrhagic cystitis

3000ml/day fluid intake unless contraindicated void q2-4 hours day, q hours night can also cause sinus drainage, slow infusion oxaliplatin - Correct Answer-hang with D5W cold sensitivity (Ixnay on the ice, okay?) irinotecan - Correct Answer- diarrhea (I run to the can) nephrotoxic - Correct Answer-avastin - protein in urine cisplatin zometa hypersensitivity reactions - Correct Answer-taxol rituxan and other MAbs herceptin zometa - Correct Answer-know creatinine prior run over at least 15 mins osteonecrosis of jaw taxol - Correct Answer-titrate first couple doses peripheral neuropathy cryotherapy need filtered

line (Are YEW going to react?) avastin - Correct Answer-MAb - angiogenesis inhibitor

palonosetron long half-life ( hours) kytril - Correct Answer-granistron

zofran - Correct Answer-ondansetron aprepitant - Correct Answer- emend stays in body 5 days prochlorperazine - Correct Answer-compazine 5-FU Fluorouracil - Correct Answer-HA, weakness, muscle aches, hand/foot syndrome, darkening skin/nails, decreased appetite, alopecia, diarrhea, neutropenia, mucositis, liver function Adriamycin/Doxorubicin - Correct Answer-vesicant, red urine/sweat, N/V, alopecia, nail changes/sensitivity, myelosuppression, anorexia, cardiotoxic - ECHO q12 weeks, watch EF change from baseline chew ice during administration to reduce mucositis Alimta Permetrexed - Correct Answer-lung, mesothelioma (asbestos) 10m infusion, q3 weeks depletes B12 and folic acid PO folic acid daily, q9 week B12 injection and 1 week prior to infusion 4mg oral steroid day prior, of and after infusion N/V, diarrhea, mucositis, rash

  • use steroids Leucovorin - Correct Answer-closely related to folic acid head and neck, colorectal used to help 5-FU and also protects normal cells in bone marrow and digestive tract from chemotherapy agents Leuprolid e Eligard Lupron - Correct Answer-hormone antagonist prostate, uterine fibroids, endometriosis stops the release of testosterone and estrogen subsequently slows cancer cells that rely on these hormones ice or spray prior for large bore needle Navelbine Vinorelbine - Correct Answer-plant alkaloid
  • vinca lung, breast N/V,constipation, peripheral neuropathy, fatigue, weakness Neulasta Pegfilgrastim - Correct Answer-granulocyte-colony stimulating factor leukopenia stimulates bone marrow to make more neutrophils one injection per cycle of chemo can cause bone marrow ache - hips, femur,
  • take tylenol Rare: spleen enlargement - swelling left side under ribs, pain left shoulder, very low WBC or sepsis 1st injection, stay for 20m, watch for hives, rash, facial edema, NV, ARDS, anaphylaxis Mucositis - Correct Answer-Inflammation, sloughing and ulceration of G.I. system, specifically oral mucosa. Susceptible d/t G.I. tract's rapidly dividing cells. Most commonly caused by alkylating agents, anti-tumor abx, head/neck radiation, bone marrow transplant,Cytoxan, DTIC, -platins S/S: pain, xerostomia, thick saliva, erythema, edema, pseudomembranes, ulcerations Tx: use soft bristle brush 4x/day, Biotin, salt/soda rinses, BMX Alopecia - Correct Answer-Hair follicles are susceptible to chemotherapy d/t their mitotic activity. Scalp hair is most senstive, then male beards, eyebrows, axilla, pubis and fine hair. Hair loss occurs 2-3 weeks after first exposure. Regrowth begins within 3- months and can be different texture, color, consistency. Choose wig prior to hair loss so that good stye match can be chosen. Peripheral Neuropathy - Correct Answer-Chemotherapy-induced numbness, tingling, pain. Caused by damage to nerve fibers thru demyelination or axonal degeneration, tumors, co- morbidities S/S: pain - burning, stabbing, sharp, electric. Loss of dexterity, extreme sensitivity to touch. Tx: B supplements, tylenol, NSAIDs, Xerostomia - Correct Answer-Dry mouth, especially with head/neck cancer and radiation. Salivary glands can become atrophic and fibrotic. Saliva can be thick, ropy, tenacious. S/S: dysphagia, dry mouth, gingival bleeding, ulcerations, weight loss, pain, tastechanges, impaired speech, infection, pain Tx: artificial saliva, viscous lidocaine, biotene, brush 3-4x daily; dry mouth can lead to dental caries, Hand/Foot Syndrome - Correct Answer-Side effect of some chemotherapy. Hand-foot syndrome causes redness, swelling, and pain on the palms of the hands and/or the soles of the feet. Sometimes blisters appear. S/S: Erythema, swelling, sensation of tingling or burning, tenderness,skin tightness, thick calluses and blisters on the palms/soles Tx: topical anesthetics, moisturizing creams, ibuprofen, ice packs during infusionLimit exposure of hands/feet to heat, friction. Don't go barefoot; use thick socks/slippers anemia - Correct Answer-Hgb < 11g platelets - Correct Answer-150,000 - 350,

WBCs - Correct Answer-4.5- neutropenic - Correct Answer-ANC > 1, creatinine - Correct Answer-0.7-1.3mg/dL chemical waste product of creatine, a chemical made by the body, used to supply energy mainly to muscles test for kidney function Hemoglobin - Correct Answer-female 12- 16g/dL male 14-17g/dL BUN (blood urea nitrogen) - Correct Answer-6- 20mg/dL formed when protein breaks down test for kidney function